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New ideas on limitations to VO2max.

VO2max indicates maximal oxidative metabolic capacity (unfit subjects) or maximal O2 supply (athletes). The latter reflects integration of all transport steps from air to cytochromes. Every step contributes something; the importance of each contribution varies with conditions. Cardiac output seems most important at sea level; at higher altitudes, lung/muscle diffusion are more critical.[1]

References

  1. New ideas on limitations to VO2max. Wagner, P.D. Exercise and sport sciences reviews. (2000) [Pubmed]
 
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