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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Neurosteroids and brain sexual differentiation.

There is new evidence that the brain of developing songbirds can synthesize estradiol de novo. In males, this neurally derived estrogen might masculinize a connection within the neural song system. These results challenge traditional concepts about mechanisms of brain sexual differentiation and reveal a significant function for neurosteroids.[1]


  1. Neurosteroids and brain sexual differentiation. Schlinger, B.A., Soma, K.K., London, S.E. Trends Neurosci. (2001) [Pubmed]
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