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Chinnadurai, G.

Chinnadurai,

CtBP, an unconventional transcriptional corepressor in development and oncogenesis.

CtBP family proteins are conserved among vertebrates and invertebrates and function as transcriptional corepressors. They repress transcription in a histone deacetylase-dependent or -independent manner. CtBPs play important roles during development and oncogenesis. In this review, their unusual properties, the mechanisms of transcriptional repression, regulation, and their biological functions are discussed.[1]

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CtBP, an unconventional transcriptional corepressor in development and oncogenesis. Chinnadurai, G. Mol. Cell (2002) [Pubmed]

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