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Lima, C.D.

Regulating UBP-mediated ubiquitin deconjugation.

The first crystal structures have been obtained for a UBP domain both alone and in complex with ubiquitin aldehyde, thus providing a framework for structural conservation throughout the UBP protease family. Comparison of the structures provides substantial insight into ubiquitin-mediated activation of UBP protease activity, a process that potentially regulates substrate-dependent ubiquitin deconjugation.[1]

References

Regulating UBP-mediated ubiquitin deconjugation. Lima, C.D. Structure (Camb.) (2003) [Pubmed]

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