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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Efficacy of a single, weekly dose of recombinant erythropoietin in myelodysplastic syndromes.

Thirteen patients with low-to-intermediate risk myelodysplastic syndrome (MDS) received recombinant erythropoietin (r-EPO) at the single, weekly dose of 40.000 U for at least 8 weeks. Five patients (38.4%) achieved a major erythroid response (increased haemoglobin levels > 2 g/dl and/or transfusion independence), which is currently maintained after 3-11 months, without modification of r-EPO dose. This study suggests that 40.000 U r-EPO given once a week may be at least as effective as the more frequent (daily or three times a week) administrations of the drug usually employed in MDS patients.[1]

References

  1. Efficacy of a single, weekly dose of recombinant erythropoietin in myelodysplastic syndromes. Musto, P., Falcone, A., Sanpaolo, G., Bodenizza, C., La Sala, A., Perla, G., Carella, A.M. Br. J. Haematol. (2003) [Pubmed]
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