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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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New members of the tomato ERF family show specific expression pattern and diverse DNA-binding capacity to the GCC box element.

Four new members of the ERF (ethylene-response factor) family of plant-specific DNA-binding (GCC box) factors were isolated from tomato fruit (LeERF1-4). Phylogenetic analysis indicated that LeERF2 belongs to a new ERF class, characterized by a conserved N-terminal signature sequence. Expression patterns and cis/trans binding affinities differed between the LeERFs. Combining experimental data and modeled three-dimensional analysis, it was shown that binding affinity of the LeERFs was affected by both the variation of nucleotides surrounding the DNA cis-element sequence and the nature of critical amino acid residues within the ERF domain.[1]

References

  1. New members of the tomato ERF family show specific expression pattern and diverse DNA-binding capacity to the GCC box element. Tournier, B., Sanchez-Ballesta, M.T., Jones, B., Pesquet, E., Regad, F., Latché, A., Pech, J.C., Bouzayen, M. FEBS Lett. (2003) [Pubmed]
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