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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

New monodentate chiral phosphite ligands for asymmetric hydrogenation.

We report the synthesis of new chiral monodentate phosphite ligands with a biphenyl backbone, the axial chirality of which is introduced early in the synthesis and locked by a chiral alkylenedioxy bridge. We also describe results obtained with these ligands in rhodium-catalysed asymmetric hydrogenation of various substrates.[1]

References

  1. New monodentate chiral phosphite ligands for asymmetric hydrogenation. Hannen, P., Militzer, H.C., Vogl, E.M., Rampf, F.A. Chem. Commun. (Camb.) (2003) [Pubmed]
 
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