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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

A protein interaction domain contacts RNA in the prespliceosome.

SR proteins bind to exons and recruit the spliceosome via protein interactions mediated by an arginine-serine-rich (RS) domain. In this issue of Molecular Cell, demonstrate that the RS domain of SR proteins contacts the pre-mRNA branchpoint, indicating that these domains participate in both protein and RNA interactions.[1]


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