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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Neuhaus, O. et al.

Oliver Neuhaus, Bernd C. Kieseier, Hans-Peter Hartung,

Therapeutic role of mitoxantrone in multiple sclerosis.

Mitoxantrone is approved by several health authorities for treatment of active forms of relapsing-remitting or secondary progressive multiple sclerosis (SPMS). This review provides an outline on relevant preclinical as well as clinical studies, places mitoxantrone in the context of other therapeutic approaches against multiple sclerosis (MS), and discusses relevant side effects. The current knowledge of the putative mechanisms of action of the compound is discussed.[1]

References

Therapeutic role of mitoxantrone in multiple sclerosis. Neuhaus, O., Kieseier, B.C., Hartung, H.P. Pharmacol. Ther. (2006) [Pubmed]

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