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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Untranslated region haplotype in dysbindin gene: analysis in schizophrenia.

Genome-scans performed in schizophrenia families have provided evidence for region 6p24-21 where variability may confer susceptibility to schizophrenia. Recent studies have implicated that gene DTNBP1 (dysbindin) in this region is strongly associated with schizophrenia. In a family based association study we investigated three markers located in the untranslated region of the DTNBP1 gene: rs909706, rs1047631 and rs742106. The sample size of our study is 117 families. No biased transmission towards the disorder was detected by haplotype analysis using TRANSMIT.[1]

References

  1. Untranslated region haplotype in dysbindin gene: analysis in schizophrenia. De Luca, V., Voineskos, D., Shinkai, T., Wong, G., Kennedy, J.L. Journal of neural transmission (Vienna, Austria : 1996) (2005) [Pubmed]
 
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