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Hombría, J.C. et al.

Hombría, Sotillos,

JAK/ STAT signalling: STAT cannot play with Ken and Barbie.

Transcriptional responses to the activation of a signalling pathway are cell-specific. New data show that the sequence-specific transcriptional repressors of the KEN/BCL-6 family play an important role in the selection of STAT targets in vertebrates and invertebrates, indicating that all STAT proteins may share this ancestral mechanism.[1]

References

JAK/STAT signalling: STAT cannot play with Ken and Barbie. Hombría, J.C., Sotillos, S. Curr. Biol. (2006) [Pubmed]

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