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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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 Sears,  
 

Severe chronic asthma.

Persistent childhood asthma is more common in females with atopy with an early onset and may result in significant impairment of lung function. Pathological changes in severe chronic asthma in childhood are only partially defined and correlation between pathology, response to treatment and persistence is imprecise. Failure to respond to usual therapies requires careful consideration of differential diagnosis, type of inflammation present, compliance with therapy, and continuing monitoring and re-assessment.[1]

References

  1. Severe chronic asthma. Sears, M.R. Paediatric respiratory reviews. (2006) [Pubmed]
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