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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Sequence analysis of the glycoprotein E gene of varicella-zoster virus strains of clades 1, 3 and 5.

Eighty-six varicella-zoster virus (VZV) strains of clades 1, 3 and 5, isolated from varicella and zoster patients in Germany, were analyzed by sequencing the glycoprotein E gene. Four novel non-synonymous and 10 novel synonymous mutations were detected. Of these, two synonymous (C513T, C885T) and two non-synonymous mutations (T485G, C524T) were located within the coding regions of e1 and c1. The profile of single-nucleotide polymorphisms was found to be significantly associated with the VZV clades 1, 3 and 5.[1]

References

  1. Sequence analysis of the glycoprotein E gene of varicella-zoster virus strains of clades 1, 3 and 5. Sauerbrei, A., Wiesener, N., Zell, R., Wutzler, P. Arch. Virol. (2011) [Pubmed]
 
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