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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

IBD: of mice and men-shedding new light on IL-13 activity in IBD.

a recent study in a mouse model of colitis has demonstrated that interleukin (Il)‑13, through inhibition of the mixed type 1 and type 17 T‑helper cell inflammatory response, has a protective effect. the decoyreceptor Il‑13rα2 inhibits this protective effect, suggesting blockade of Il‑13rα2 as a potential therapy for patients with IBD.[1]

References

  1. IBD: of mice and men-shedding new light on IL-13 activity in IBD. Danese, S. Nat. Rev. Gastroenterol. Hepatol (2011) [Pubmed]
 
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