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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

HLA-antigens in a Tunisian familial chondrocalcinosis.

Thirty members of a Tunisian family with hereditary chondrocalcinosis were typed for HLA-A, B, and DR antigens: 7 affected and 23 unaffected subjects in three consecutive generations. The haplotype A1 B12 DR3 was found in all affected subjects and in 8 unaffected members. Chondrocalcinosis in this family may be associated with the haplotype A1 B12 DR3. The mode of transmission was autosomal dominant with incomplete penetrance.[1]


  1. HLA-antigens in a Tunisian familial chondrocalcinosis. Hamza, M., Ayed, K., Bardi, R., Gebuhrer, L., Betuel, H., Bardin, T., Plaetke, R., Lathrop, M. Dis. Markers (1990) [Pubmed]
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