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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Spontaneous switching of the sucrose-promoted colony phenotype in Streptococcus sanguis.

Streptococcus sanguis on media containing 3% sucrose gives rise to characteristic hard cohesive colonies (designated Spp+). Populations of Spp+ bacteria (strain Challis) on sucrose media switch to a soft noncohesive phenotype (designated Spp-) at a frequency of 10(-4) to 10(-3). Spp- bacteria switch back to Spp+ bacteria at a similar frequency. Successive rounds of Spp variation were observed. The Spp phenotypic switch was associated with changes in extracellular glucosyltransferase activity.[1]

References

  1. Spontaneous switching of the sucrose-promoted colony phenotype in Streptococcus sanguis. Tardif, G., Sulavik, M.C., Jones, G.W., Clewell, D.B. Infect. Immun. (1989) [Pubmed]
 
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