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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Menstrual cycle-related sensitivity to 35% CO2 in panic patients.

In a double blind, random, cross-over design, 10 patients and seven controls inhaled one vital capacity of 35% CO2-65% O2 during their early-follicular and midluteal phases. Anxiety after CO2 intake was significantly stronger in the early-follicular phase than in the midluteal phase for patients. Controls had no anxiety reactions.[1]


  1. Menstrual cycle-related sensitivity to 35% CO2 in panic patients. Perna, G., Brambilla, F., Arancio, C., Bellodi, L. Biol. Psychiatry (1995) [Pubmed]
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