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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Trachyspic acid, a new metabolite produced by Talaromyces trachyspermus, that inhibits tumor cell heparanase: taxonomy of the producing strain, fermentation, isolation, structural elucidation, and biological activity.

Trachyspic acid, a new metabolite that inhibited heparanase, was isolated from the culture broth of Talaromyces trachyspermus SANK 12191. Its structure was deduced from NMR spectral analyses and chemical reactions as a tricarboxylic acid derivative containing a spiroketal. The IC50 value of trachyspic acid against heparanase was 36 microM.[1]

References

  1. Trachyspic acid, a new metabolite produced by Talaromyces trachyspermus, that inhibits tumor cell heparanase: taxonomy of the producing strain, fermentation, isolation, structural elucidation, and biological activity. Shiozawa, H., Takahashi, M., Takatsu, T., Kinoshita, T., Tanzawa, K., Hosoya, T., Furuya, K., Takahashi, S., Furihata, K., Seto, H. J. Antibiot. (1995) [Pubmed]
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