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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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1-N-Alkyl analogs of butirosin.

Butirosin (Ia), 5''-amino-5''-deoxy-(Ic), 3',4'-dideoxy-(Ie), and 5''-amino-3',4',5''-trideoxy-butirosin A (If) were converted into the corresponding 1'''-deoxo derivatives, Ib, Id, Ig, and Ih by borane reduction. In addition, xylostasin (IIIa) was converted into its 1-N-ethyl derivative (IIIb) by reductive ethylation. Their antibacterial activities were discussed.[1]

References

  1. 1-N-Alkyl analogs of butirosin. Hayashi, T., Saeki, H., Takeda, N., Ohko, E. J. Antibiot. (1979) [Pubmed]
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