Gene Review:
SETX - senataxin
Homo sapiens
Synonyms:
ALS4, AOA2, Amyotrophic lateral sclerosis 4 protein, KIAA0625, SCAR1, ...
- Senataxin, the ortholog of a yeast RNA helicase, is mutant in ataxia-ocular apraxia 2. Moreira, M.C., Klur, S., Watanabe, M., Németh, A.H., Le Ber, I., Moniz, J.C., Tranchant, C., Aubourg, P., Tazir, M., Schöls, L., Pandolfo, M., Schulz, J.B., Pouget, J., Calvas, P., Shizuka-Ikeda, M., Shoji, M., Tanaka, M., Izatt, L., Shaw, C.E., M'Zahem, A., Dunne, E., Bomont, P., Benhassine, T., Bouslam, N., Stevanin, G., Brice, A., Guimarães, J., Mendonça, P., Barbot, C., Coutinho, P., Sequeiros, J., Dürr, A., Warter, J.M., Koenig, M. Nat. Genet. (2004)
- Linkage of the gene for an autosomal dominant form of juvenile amyotrophic lateral sclerosis to chromosome 9q34. Chance, P.F., Rabin, B.A., Ryan, S.G., Ding, Y., Scavina, M., Crain, B., Griffin, J.W., Cornblath, D.R. Am. J. Hum. Genet. (1998)
- Autosomal recessive ataxia with peripheral neuropathy and elevated AFP: novel mutations in SETX. Asaka, T., Yokoji, H., Ito, J., Yamaguchi, K., Matsushima, A. Neurology (2006)
- Atypical presentation of ataxia-oculomotor apraxia type 1. Shahwan, A., Byrd, P.J., Taylor, A.M., Nestor, T., Ryan, S., King, M.D. Developmental medicine and child neurology. (2006)
- Autosomal dominant juvenile amyotrophic lateral sclerosis and distal hereditary motor neuronopathy with pyramidal tract signs: synonyms for the same disorder? De Jonghe, P., Auer-Grumbach, M., Irobi, J., Wagner, K., Plecko, B., Kennerson, M., Zhu, D., De Vriendt, E., Van Gerwen, V., Nicholson, G., Hartung, H.P., Timmerman, V. Brain (2002)
- DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4). Chen, Y.Z., Bennett, C.L., Huynh, H.M., Blair, I.P., Puls, I., Irobi, J., Dierick, I., Abel, A., Kennerson, M.L., Rabin, B.A., Nicholson, G.A., Auer-Grumbach, M., Wagner, K., De Jonghe, P., Griffin, J.W., Fischbeck, K.H., Timmerman, V., Cornblath, D.R., Chance, P.F. Am. J. Hum. Genet. (2004)
- Mutations in senataxin responsible for Quebec cluster of ataxia with neuropathy. Duquette, A., Roddier, K., McNabb-Baltar, J., Gosselin, I., St-Denis, A., Dicaire, M.J., Loisel, L., Labuda, D., Marchand, L., Mathieu, J., Bouchard, J.P., Brais, B. Ann. Neurol. (2005)
- Objective assessment of keloid scars with three-dimensional imaging: quantifying response to intralesional steroid therapy. Ardehali, B., Nouraei, S.A., Van Dam, H., Dex, E., Wood, S., Nduka, C. Plast. Reconstr. Surg. (2007)
- Autosomal dominant juvenile amyotrophic lateral sclerosis. Rabin, B.A., Griffin, J.W., Crain, B.J., Scavina, M., Chance, P.F., Cornblath, D.R. Brain (1999)
- Senataxin, the yeast Sen1p orthologue: characterization of a unique protein in which recessive mutations cause ataxia and dominant mutations cause motor neuron disease. Chen, Y.Z., Hashemi, S.H., Anderson, S.K., Huang, Y., Moreira, M.C., Lynch, D.R., Glass, I.A., Chance, P.F., Bennett, C.L. Neurobiol. Dis. (2006)
- Comparison between Candida albicans agglutinin-like sequence gene expression patterns in human clinical specimens and models of vaginal candidiasis. Cheng, G., Wozniak, K., Wallig, M.A., Fidel, P.L., Trupin, S.R., Hoyer, L.L. Infect. Immun. (2005)
- Analysis of the Candida albicans Als2p and Als4p adhesins suggests the potential for compensatory function within the Als family. Zhao, X., Oh, S.H., Yeater, K.M., Hoyer, L.L. Microbiology (Reading, Engl.) (2005)
- Reliability and validity testing of the Patient and Observer Scar Assessment Scale in evaluating linear scars after breast cancer surgery. Truong, P.T., Lee, J.C., Soer, B., Gaul, C.A., Olivotto, I.A. Plast. Reconstr. Surg. (2007)
- Reconstructive surgery with Integra dermal regeneration template: histologic study, clinical evaluation, and current practice. Moiemen, N.S., Vlachou, E., Staiano, J.J., Thawy, Y., Frame, J.D. Plast. Reconstr. Surg. (2006)