Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

PRRC2C - proline-rich coiled-coil 2C

Homo sapiens

Synonyms: BAT2 domain-containing protein 1, BAT2-iso, BAT2D1, BAT2L2, HBV X-transactivated gene 2 protein, ...

Huang, W.C. et al.

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Disease relevance of BAT2D1

Immunohistochemistry (IHC) demonstrated KIAA1096 expression in nonmalignant bladder mucosa tissue but apparent upregulation in invasive transitional cell carcinoma [1].

High impact information on BAT2D1

KIAA1096, a gene on chromosome 1q, is amplified and overexpressed in bladder cancer [1].
The KIAA1096 gene is located at 1q23-24 with no overexpression or amplification in normal urothelium, but was significantly upregulated in 30% of tumors (P = 0.0001) [1].
In summary, KIAA1096 is a gene situated at 1q23-24, which demonstrated a pattern of RNA and DNA expression consistent with the 38% expression of cytogenetic amplification noted on previous studies [1].

References

KIAA1096, a gene on chromosome 1q, is amplified and overexpressed in bladder cancer. Huang, W.C., Taylor, S., Nguyen, T.B., Tomaszewski, J.E., Libertino, J.A., Malkowicz, S.B., McGarvey, T.W. DNA Cell Biol. (2002) [Pubmed]

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