Gene Review:
GPR37 - G protein-coupled receptor 37 (endothelin...
Homo sapiens
Synonyms:
EDNRBL, ETBR-LP-1, Endothelin B receptor-like protein 1, G-protein coupled receptor 37, PAELR, ...
- Pael receptor, endoplasmic reticulum stress, and Parkinson's disease. Takahashi, R., Imai, Y. J. Neurol. (2003)
- Suppressive effects of 4-phenylbutyrate on the aggregation of Pael receptors and endoplasmic reticulum stress. Kubota, K., Niinuma, Y., Kaneko, M., Okuma, Y., Sugai, M., Omura, T., Uesugi, M., Uehara, T., Hosoi, T., Nomura, Y. J. Neurochem. (2006)
- Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. Kitao, Y., Imai, Y., Ozawa, K., Kataoka, A., Ikeda, T., Soda, M., Nakimawa, K., Kiyama, H., Stern, D.M., Hori, O., Wakamatsu, K., Ito, S., Itohara, S., Takahashi, R., Ogawa, S. Hum. Mol. Genet. (2007)
- An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Imai, Y., Soda, M., Inoue, H., Hattori, N., Mizuno, Y., Takahashi, R. Cell (2001)
- Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Yang, Y., Nishimura, I., Imai, Y., Takahashi, R., Lu, B. Neuron (2003)
- Pael-R is accumulated in Lewy bodies of Parkinson's disease. Murakami, T., Shoji, M., Imai, Y., Inoue, H., Kawarabayashi, T., Matsubara, E., Harigaya, Y., Sasaki, A., Takahashi, R., Abe, K. Ann. Neurol. (2004)
- Thioredoxin suppresses Parkin-associated endothelin receptor-like receptor-induced neurotoxicity and extends longevity in Drosophila. Umeda-Kameyama, Y., Tsuda, M., Ohkura, C., Matsuo, T., Namba, Y., Ohuchi, Y., Aigaki, T. J. Biol. Chem. (2007)
- Cloning of GPR37, a gene located on chromosome 7 encoding a putative G-protein-coupled peptide receptor, from a human frontal brain EST library. Marazziti, D., Golini, E., Gallo, A., Lombardi, M.S., Matteoni, R., Tocchini-Valentini, G.P. Genomics (1997)
- A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death. Imai, Y., Soda, M., Murakami, T., Shoji, M., Abe, K., Takahashi, R. J. Biol. Chem. (2003)
- The pathological role of Pael-receptor/GPR37 in AR-JP. Takahahshi, R. Parkinsonism Relat. Disord. (2006)
- The neuropeptide head activator is a high-affinity ligand for the orphan G-protein-coupled receptor GPR37. Rezgaoui, M., Süsens, U., Ignatov, A., Gelderblom, M., Glassmeier, G., Franke, I., Urny, J., Imai, Y., Takahashi, R., Schaller, H.C. J. Cell. Sci. (2006)
- Molecular cloning and chromosomal localization of the mouse Gpr37 gene encoding an orphan G-protein-coupled peptide receptor expressed in brain and testis. Marazziti, D., Gallo, A., Golini, E., Matteoni, R., Tocchini-Valentini, G.P. Genomics (1998)
- A novel endothelin receptor type-B-like gene enriched in the brain. Zeng, Z., Su, K., Kyaw, H., Li, Y. Biochem. Biophys. Res. Commun. (1997)