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GPR1  -  G protein-coupled receptor 1

Homo sapiens

Synonyms: G-protein coupled receptor 1
 
 
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Disease relevance of GPR1

 

Psychiatry related information on GPR1

 

High impact information on GPR1

 

Chemical compound and disease context of GPR1

 

Biological context of GPR1

 

Anatomical context of GPR1

 

Associations of GPR1 with chemical compounds

 

Physical interactions of GPR1

 

Enzymatic interactions of GPR1

 

Regulatory relationships of GPR1

 

Other interactions of GPR1

 

Analytical, diagnostic and therapeutic context of GPR1

References

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  2. An orphan G protein-coupled receptor, GPR1, acts as a coreceptor to allow replication of human immunodeficiency virus types 1 and 2 in brain-derived cells. Shimizu, N., Soda, Y., Kanbe, K., Liu, H.Y., Jinno, A., Kitamura, T., Hoshino, H. J. Virol. (1999) [Pubmed]
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  19. Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer. Goetzl, E.J., Dolezalova, H., Kong, Y., Hu, Y.L., Jaffe, R.B., Kalli, K.R., Conover, C.A. Cancer Res. (1999) [Pubmed]
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  21. Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase. Eggerickx, D., Denef, J.F., Labbe, O., Hayashi, Y., Refetoff, S., Vassart, G., Parmentier, M., Libert, F. Biochem. J. (1995) [Pubmed]
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  23. Human interferon-gamma-inducible protein 10 (IP-10) inhibits constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor. Geras-Raaka, E., Varma, A., Ho, H., Clark-Lewis, I., Gershengorn, M.C. J. Exp. Med. (1998) [Pubmed]
  24. Infection of mesangial cells with HIV and SIV: identification of GPR1 as a coreceptor. Tokizawa, S., Shimizu, N., Hui-Yu, L., Deyu, F., Haraguchi, Y., Oite, T., Hoshino, H. Kidney Int. (2000) [Pubmed]
  25. Heterologous desensitization of T cell functions by CCR5 and CXCR4 ligands: inhibition of cellular signaling, adhesion and chemotaxis. Hecht, I., Cahalon, L., Hershkoviz, R., Lahat, A., Franitza, S., Lider, O. Int. Immunol. (2003) [Pubmed]
  26. Functional splice variants of the type II G protein-coupled receptor (VPAC2) for vasoactive intestinal peptide in mouse and human lymphocytes. Miller, A.L., Verma, D., Grinninger, C., Huang, M.C., Goetzl, E.J. Ann. N. Y. Acad. Sci. (2006) [Pubmed]
  27. Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection. Farzan, M., Choe, H., Martin, K., Marcon, L., Hofmann, W., Karlsson, G., Sun, Y., Barrett, P., Marchand, N., Sullivan, N., Gerard, N., Gerard, C., Sodroski, J. J. Exp. Med. (1997) [Pubmed]
  28. HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Feng, Y., Broder, C.C., Kennedy, P.E., Berger, E.A. Science (1996) [Pubmed]
  29. A synthetic peptide derived from human immunodeficiency virus type 1 gp120 downregulates the expression and function of chemokine receptors CCR5 and CXCR4 in monocytes by activating the 7-transmembrane G-protein-coupled receptor FPRL1/LXA4R. Deng, X., Ueda, H., Su, S.B., Gong, W., Dunlop, N.M., Gao, J.L., Murphy, P.M., Wang, J.M. Blood (1999) [Pubmed]
  30. CXCL-12/stromal cell-derived factor-1alpha transactivates HER2-neu in breast cancer cells by a novel pathway involving Src kinase activation. Cabioglu, N., Summy, J., Miller, C., Parikh, N.U., Sahin, A.A., Tuzlali, S., Pumiglia, K., Gallick, G.E., Price, J.E. Cancer Res. (2005) [Pubmed]
  31. Direct mapping of an agonist-binding domain within the parathyroid hormone/parathyroid hormone-related protein receptor by photoaffinity crosslinking. Zhou, A.T., Bessalle, R., Bisello, A., Nakamoto, C., Rosenblatt, M., Suva, L.J., Chorev, M. Proc. Natl. Acad. Sci. U.S.A. (1997) [Pubmed]
  32. Ascaris suum-derived products induce human neutrophil activation via a G protein-coupled receptor that interacts with the interleukin-8 receptor pathway. Falcone, F.H., Rossi, A.G., Sharkey, R., Brown, A.P., Pritchard, D.I., Maizels, R.M. Infect. Immun. (2001) [Pubmed]
  33. R7BP Augments the Function of RGS7{middle dot}Gbeta5 Complexes by a Plasma Membrane-targeting Mechanism. Drenan, R.M., Doupnik, C.A., Jayaraman, M., Buchwalter, A.L., Kaltenbronn, K.M., Huettner, J.E., Linder, M.E., Blumer, K.J. J. Biol. Chem. (2006) [Pubmed]
  34. Intracellular calcium mobilization in response to the activation of human wild-type and chimeric gonadotropin receptors. Lee, P.S., Buchan, A.M., Hsueh, A.J., Yuen, B.H., Leung, P.C. Endocrinology (2002) [Pubmed]
  35. Increased expression of urotensin II and its cognate receptor GPR14 in atherosclerotic lesions of the human aorta. Bousette, N., Patel, L., Douglas, S.A., Ohlstein, E.H., Giaid, A. Atherosclerosis (2004) [Pubmed]
  36. The amino terminus with a conserved glutamic acid of G protein-coupled receptor kinases is indispensable for their ability to phosphorylate photoactivated rhodopsin. Yu, Q.M., Cheng, Z.J., Gan, X.Q., Bao, G.B., Li, L., Pei, G. J. Neurochem. (1999) [Pubmed]
  37. G protein-coupled receptor kinase 2 and beta-arrestins are recruited to FSH receptor in stimulated rat primary Sertoli cells. Marion, S., Kara, E., Crepieux, P., Piketty, V., Martinat, N., Guillou, F., Reiter, E. J. Endocrinol. (2006) [Pubmed]
  38. G-protein-coupled receptor kinase activity is increased in hypertension. Gros, R., Benovic, J.L., Tan, C.M., Feldman, R.D. J. Clin. Invest. (1997) [Pubmed]
  39. Stromal-cell derived factor is expressed by dendritic cells and endothelium in human skin. Pablos, J.L., Amara, A., Bouloc, A., Santiago, B., Caruz, A., Galindo, M., Delaunay, T., Virelizier, J.L., Arenzana-Seisdedos, F. Am. J. Pathol. (1999) [Pubmed]
  40. Characterization of RANTES- and aminooxypentane-RANTES-triggered desensitization signals reveals differences in recruitment of the G protein-coupled receptor complex. Vila-Coro, A.J., Mellado, M., Martín de Ana, A., Martínez-A, C., Rodríguez-Frade, J.M. J. Immunol. (1999) [Pubmed]
  41. Identification and functional expression of a receptor selectively recognizing parathyroid hormone, the PTH2 receptor. Usdin, T.B., Gruber, C., Bonner, T.I. J. Biol. Chem. (1995) [Pubmed]
  42. Src-mediated RGS16 tyrosine phosphorylation promotes RGS16 stability. Derrien, A., Zheng, B., Osterhout, J.L., Ma, Y.C., Milligan, G., Farquhar, M.G., Druey, K.M. J. Biol. Chem. (2003) [Pubmed]
  43. Mechanisms and modulation of pituitary adenylate cyclase-activating protein-induced calcium mobilization in human neutrophils. Harfi, I., Sariban, E. Ann. N. Y. Acad. Sci. (2006) [Pubmed]
  44. Use of GPR1, GPR15, and STRL33 as coreceptors by diverse human immunodeficiency virus type 1 and simian immunodeficiency virus envelope proteins. Edinger, A.L., Hoffman, T.L., Sharron, M., Lee, B., O'Dowd, B., Doms, R.W. Virology (1998) [Pubmed]
  45. HIV-1 co-receptor expression on trophoblastic cells from early placentas and permissivity to infection by several HIV-1 primary isolates. Mognetti, B., Moussa, M., Croitoru, J., Menu, E., Dormont, D., Roques, P., Chaouat, G. Clin. Exp. Immunol. (2000) [Pubmed]
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  47. Generation of a constitutively active mutant of human GPR48/LGR4, a G-protein-coupled receptor. Gao, Y., Kitagawa, K., Shimada, M., Uchida, C., Hattori, T., Oda, T., Kitagawa, M. Hokkaido Igaku Zasshi (2006) [Pubmed]
  48. Development of surface-based assays for transmembrane proteins: selective immobilization of functional CCR5, a G protein-coupled receptor. Silin, V.I., Karlik, E.A., Ridge, K.D., Vanderah, D.J. Anal. Biochem. (2006) [Pubmed]
  49. Neurotensin receptor-1 and -3 complex modulates the cellular signaling of neurotensin in the HT29 cell line. Martin, S., Navarro, V., Vincent, J.P., Mazella, J. Gastroenterology (2002) [Pubmed]
  50. Techniques: GPCR assembly, pharmacology and screening by flow cytometry. Waller, A., Simons, P.C., Biggs, S.M., Edwards, B.S., Prossnitz, E.R., Sklar, L.A. Trends Pharmacol. Sci. (2004) [Pubmed]
  51. A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers. Waldhoer, M., Fong, J., Jones, R.M., Lunzer, M.M., Sharma, S.K., Kostenis, E., Portoghese, P.S., Whistler, J.L. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
 
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