Psychiatry related information on SCHIP1

• Mental health benefits under SCHIP [1].

High impact information on SCHIP1

• We identified the p110 subunit of the eukaryotic initiation factor 3 (eIF3c) as a schwannomin interacting protein [2].
• Immunofluorescent staining of transiently transfected cells shows a partial colocalization of SCHIP-1 and schwannomin, beneath the cytoplasmic membrane [3].
• Our observations suggest that SCHIP-1 interaction with schwannomin is regulated by conformational changes in schwannomin, possibly induced by posttranslational modifications, alternative splicing, or mutations [3].
• SCHIP: statistics for chromosome interphase positioning based on interchange data [4].
• This study characterizes a novel human fusion gene named IQCJ-SCHIP1 [5].

Biological context of SCHIP1

• Assignment of the schwannomin-interacting protein 1 (SCHIP1) gene to human chromosome band 3q25 by in situ hybridization and with somatic cell hybrids [6].
• IQCJ-SCHIP1 is located on the chromosome 3q25 and comprises a 1692-bp transcript encompassing 11 exons spanning 828kb of the genomic DNA [5].
• IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein [5].

Anatomical context of SCHIP1

• Protein encoded by the IQCJ-SCHIP1 gene was localized to cytoplasm and actin-rich regions and in differentiated PC12 cells was also seen in neurite extensions [5].

Analytical, diagnostic and therapeutic context of SCHIP1

• CONCLUSIONS: Because adolescents constitute a sizeable proportion of the SCHIP population, states and managed care organizations need to consider ways to increase the participants of adolescent providers and to identify various financial and other incentives to address the serious shortages in mental health services and dental care [7].
• Options for prenatal care under Medicaid and SCHIP [8].

References