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Gene Review

myoF  -  class I myosin

Dictyostelium discoideum AX4

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High impact information on myoF

  • Clones corresponding to four of these additional loci (myoF, myoH-J) were obtained by using the isolated yeast artificial chromosomes as templates in a PCR employing degenerate primers specific for conserved regions of the myosin head [1].
  • The role of the actin cortex, the microtubule (MT) aster and their crosstalk is explored by comparing the behaviour of wild-type cells, myosin II null mutants, latrunculin A and benomyl treated cells [2].


  1. Discovery of myosin genes by physical mapping in Dictyostelium. Titus, M.A., Kuspa, A., Loomis, W.F. Proc. Natl. Acad. Sci. U.S.A. (1994) [Pubmed]
  2. Active mechanical stabilization of the viscoplastic intracellular space of Dictyostelia cells by microtubule-actin crosstalk. Heinrich, D., Sackmann, E. Acta biomaterialia. (2006) [Pubmed]
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