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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Prss33  -  protease, serine 33

Mus musculus

Synonyms: Eos, Serine protease 33, Tryptase-6, mT6, tryptase-6
 
 
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High impact information on Prss33

  • Of the three new serine proteases, mT6 is most widely expressed in tissues. mT5 is preferentially expressed in smooth muscle, whereas mMCP-11 is preferentially expressed in the spleen and bone marrow [1].
  • Although mT6 and mMCP-11 are constitutively secreted when expressed in mammalian and insect cells, mT5 remains membrane-associated [1].
  • In this modification (TE), 66% of one-cell CF1 embryos developed into blastocysts, compared to 46 and 43% for ECM and mT6, respectively [2].
 

Anatomical context of Prss33

References

  1. Mouse chromosome 17A3.3 contains 13 genes that encode functional tryptic-like serine proteases with distinct tissue and cell expression patterns. Wong, G.W., Yasuda, S., Morokawa, N., Li, L., Stevens, R.L. J. Biol. Chem. (2004) [Pubmed]
  2. In vitro development of one-cell embryos from outbred mice: influence of culture medium composition. Spindle, A. In Vitro Cell. Dev. Biol. (1990) [Pubmed]
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