Gene Review:
ADAM10 - ADAM metallopeptidase domain 10
Gallus gallus
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High impact information on ADAM10
- When a dominant-negative metalloprotease-mutant form of ADAM 10 is expressed in the ectoderm or ADAM 10 expression is knocked down with morpholinos, morphogenesis and tissue specification are altered [1].
- Chick ADAM 10 is expressed in the developing dermatome and myotome of the somite, epidermis, gut endoderm, the epithelial tissues of the kidney, liver, and heart, and in neural crest cells [1].
Biological context of ADAM10
- ADAM 10: an active metalloprotease expressed during avian epithelial morphogenesis [1].
References
- ADAM 10: an active metalloprotease expressed during avian epithelial morphogenesis. Hall, R.J., Erickson, C.A. Dev. Biol. (2003) [Pubmed]
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