Gene Review:
SH3BGR - SH3 domain binding glutamate-rich protein
Homo sapiens
Synonyms:
21-GARP, 21-glutamic acid-rich protein, SH3 domain-binding glutamic acid-rich protein, SH3BGR protein
- The identification of a novel human homologue of the SH3 binding glutamic acid-rich (SH3BGR) gene establishes a new family of highly conserved small proteins related to Thioredoxin Superfamily. Mazzocco, M., Maffei, M., Egeo, A., Vergano, A., Arrigo, P., Di Lisi, R., Ghiotto, F., Scartezzini, P. Gene (2002)
- A novel human homologue of the SH3BGR gene encodes a small protein similar to Glutaredoxin 1 of Escherichia coli. Mazzocco, M., Arrigo, P., Egeo, A., Maffei, M., Vergano, A., Di Lisi, R., Ghiotto, F., Ciccone, E., Cinti, R., Ravazzolo, R., Scartezzini, P. Biochem. Biophys. Res. Commun. (2001)
- High-resolution physical map and identification of potentially regulatory sequences of the human SH3BGR located in the Down syndrome chromosomal region. Vidal-Taboada, J.M., Bergoñon, S., Scartezzini, P., Egeo, A., Nizetic, D., Oliva, R. Biochem. Biophys. Res. Commun. (1997)
- The suppression of SH3BGRL is important for v-Rel-mediated transformation. Majid, S.M., Liss, A.S., You, M., Bose, H.R. Oncogene (2006)
- Heart morphogenesis is not affected by overexpression of the Sh3bgr gene mapping to the Down syndrome heart critical region. Sandri, C., Di Lisi, R., Picard, A., Argentini, C., Calabria, E., Myklak, K., Scartezzini, P., Schiaffino, S. Hum. Genet. (2004)
- Cloning a new human gene from chromosome 21q22.3 encoding a glutamic acid-rich protein expressed in heart and skeletal muscle. Scartezzini, P., Egeo, A., Colella, S., Fumagalli, P., Arrigo, P., Nizetic, D., Taramelli, R., Rasore-Quartino, A. Hum. Genet. (1997)