The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

UBL7  -  ubiquitin-like 7 (bone marrow stromal cell...

Homo sapiens

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on UBL7

  • In the complex structure, three residues (Met76, Ile78, and Leu99) of BMSC-UbP UBA form a trident anchoring the domain to the hydrophobic concave surface of ubiquitin defined by residues Leu8, Ile44, His68, and Val70 [1].
  • The structure determination was facilitated by using a solubility-enhancement tag (SET) GB1, immunoglobulin G binding domain 1 of Streptococcal protein G. The results show that BMSC-UbP UBA domain is primarily comprised of three alpha-helices with a hydrophobic patch defined by residues within the C terminus of helix-1, loop-1, and helix-3 [1].
  • The previously identified BMSC-UbP protein derived from bone marrow stromal cells contains a ubiquitin-associated (UBA) domain at the C terminus that has been implicated in linking cellular processes and the ubiquitin system [1].
  • The structural model of BMSC-UbP UBA domain complexed with ubiquitin was constructed by chemical shift mapping combined with the program HADDOCK, which is in agreement with the result from mutagenesis studies [1].
  • Cloning and identification of a novel ubiquitin-like protein, BMSC-UbP, from human bone marrow stromal cells [2].
 

Biological context of UBL7

 

Anatomical context of UBL7

References

  1. Solution structure of the ubiquitin-associated domain of human BMSC-UbP and its complex with ubiquitin. Chang, Y.G., Song, A.X., Gao, Y.G., Shi, Y.H., Lin, X.J., Cao, X.T., Lin, D.H., Hu, H.Y. Protein Sci. (2006) [Pubmed]
  2. Cloning and identification of a novel ubiquitin-like protein, BMSC-UbP, from human bone marrow stromal cells. Liu, S., Yu, Y., An, H., Li, N., Lin, N., Wang, W., Zhang, W., Wan, T., Cao, X. Immunol. Lett. (2003) [Pubmed]
 
WikiGenes - Universities