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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 494 documents. Results 1 - 10.

Chemical compound: ... Disease relevance of Deaza- Ado Anti- human immunodeficiency virus 1( HIV- 1) activities of 3...- deazaadenosine- treated infected chicken embryo fibroblasts. High impact information on Deaza- Ado Inhibition... and disease context of Deaza- Ado Neplanocin A( NeplA) and 3- deazaadenosine( 3DA- Ado) are both inhibitors... / Synonyms: 3dAdo
Drosophila melanogaster
Gene: ... High impact information on AdoR These developmental defects were reduced by adenosine depletion, consistent with the proposed function of the CG9753 product as an AdoR. Endogenous CG9753 transcripts were detected in the brain, imaginal discs, ring gland and salivary glands of third- instar Drosophila larvae... / Synonyms: DmAdoR; adoR; dAdoR
Chemical compound: ... AdoHcy in the same conformation as confirmed m( 5) C MTases and, while DNMT2 shares all sequence... Haemophilus influenzae, as binary complexes with either AdoMet or S- adenosyl- L- homocysteine( AdoHcy ), as a ternary complex with AdoHcy and phosphate, and as an apo form. We report here the crystal structures... / Synonyms: AdoHcy
Saccharomyces cerevisiae S288c
Gene: ... Disease relevance of ADO1 Expression in Escherichia coli of a recombinant adenosine kinase from... impact information on ADO1 Here, we present evidence that the viral proteins interact with and inactivate... and ATP. The Saccharomyces cerevisiae ADO1 gene is known to encode a homologue of eukaryotic adenosine...
Chemical compound: ... High impact information on MA- Ado In spite of this different metabolic behavior, the same order of cytotoxicity on glomerular epithelial cells in culture was observed for MA- Ado, DA- Ado and commercial PAN. DA- Ado was not a substrate for adenosine deaminase( ADA ), purine nucleoside phosphorylase( PNP...
Chemical compound: ... - methyl cytosines, presumably via the ODC/ polyamines/ decarboxylated S- adenosylmethionine( dc- Ado... of MTA was 2. 6 pmol/ well. S- Adenosylmethionine decarboxylase( AdoMetDC) is a key enzyme... substrate decarboxylated S- adenosylmethionine( dec AdoMet). Concomitantly, S- adenosylmethionine... / Synonyms: decarboxylated AdoMet
Chemical compound: ... Disease relevance of ddeAdo However, its in vitro chemotherapeutic index is higher than that of 3... of acquired immunodeficiency syndrome. ddeAdo has a weaker anti- HIV and a stronger cytostatic effect than ddAdo.... The 2 ', 3 '- unsaturated derivatives of ddDAPR and ddAdo, i. e. ddeDAPR and ddeAdo, are considerably...
Article
Chemical compound: ... Disease relevance of S- adenosylhomocysteine Impaired ability to catabolize AdoHcy may have... toxicity associated with their combined use. The crystal structures of Escherichia coli MTA/ Ado... at the AdoHcy and AdoMet concentrations found in interferon- treated cells, a preferential inhibition...

 

 
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