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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 

Your search matched a total of 96 documents. Results 1 - 10.

Homo sapiens
Gene: ... conditions for all PCR reactions, covering all of the coding exons in KCNH2 and KCNE2. No associations...Disease relevance of KCNH2 OBJECTIVES: The purpose of this research was to determine whether an intronic variant( T1945+ 6C) in KCNH2 is a disease- causing mutation, and if expanded phenotyping criteria...
Canis lupus familiaris
Gene: ... Disease relevance of KCNH2 In isolated myocytes I( Kr) frequently is small in amplitude or absent, yet KCNH2 channels and I( Kr) are targets for drug block or mutations to cause long QT syndrome. While... IKs and IKr currents in guinea pig ventricular myocytes. High impact information on KCNH2 Specific...
Mus musculus
Gene: ... Disease relevance of Kcnh2 Knockout of ERG1 B predisposes mice to episodic sinus bradycardia... information on Kcnh2 In adult ERG1 B (-/-) myocytes no I( Kr) was detected. Through homologous recombination..., with an IC50 of 54 nmol/ L. Biological context of Kcnh2 In this study, we report a detailed analysis of Kcnq1...
Rattus norvegicus
Gene: ... Psychiatry related information on Kcnh2 Abnormal expression of epilepsy- related gene ERG1/ NSF... information on Kcnh2 Thus, r- ERG1 and Src tyrosine kinase appear to exist in a signaling complex that is well... transcriptional synergy with the Jun/ Fos heterodimer( Y371V). Biological context of Kcnh2 In this first report...
Danio rerio
Gene: Synonyms: kcnh2; kcnh2l
MeSH term: ... and atrial fibrillation caused by mutation in KCNH2. Severe neurologic deficit, greater infarct volume...
Canis lupus familiaris
Gene: ... High impact information on KCND3 Electrical remodeling due to CAVB was also observed in the VS as was shown by approximately twofold lower levels in KCND3, KCNH2 and KCNQ1 mRNA( P< 0. 05) in the LVS compared to SR, thereby creating new or eliminating existing transseptal gradients....

 

 
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