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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Your search matched a total of 76 documents. Results 1 - 10.

Homo sapiens
Gene: ... ). In this study, we performed Ala- scanning mutagenesis of all Tcf4 residues in the Tcf- beta- catenin interface...A word of caution Some of the TCF4 references on this page are not about" transcription factor 4( TCF4 )" but about" T- cell factor 4" with the same synonym( TCF4, or TCF7L2 ). Please help to remove... / Synonyms: TCF-4
Mus musculus
Gene: ... Disease relevance of Tcf4 Inhibition of beta- catenin/ Tcf signaling by ectopic expression of dominant negative Tcf4 resulted in significant inhibition of growth in squamous cell carcinoma cells. The high levels of Tcf- 4 expression in mammary epithelium and mammary carcinomas may also indicate a role... / Synonyms: TCF-4; Tcf-4
Rattus norvegicus
Gene: ... Disease relevance of Tcf4 To permit rational targeting of colon tumors, we have developed replicating adenoviruses that express the viral E1B and E2 genes from promoters controlled by the Tcf4... vulnerable CA3 or dentate granule cell subfields. High impact information on Tcf4 Overexpression of beta... / Synonyms: TCF-4
Homo sapiens
Gene: ... inducible factor- 1alpha( HIF- 1alpha) competes with TCF- 4 for direct binding to beta- catenin. Mutations in the Wnt components AXIN1, AXIN2 and TCF4 have been found in microsatellite- unstable colon cancers...- like 2 gene( TCF7L2; formerly TCF4) was associated with type 2 diabetes( P= 2. 1 x 10 (- 9 )). Crystal... / Synonyms: TCF-4; TCF4; hTCF-4
Mus musculus
Gene: ... by overexpression of Axin or dominant- negative TCF4, these cells differentiate into adipocytes. Deletion of a C- terminal domain of TCF4E prevented Cdx1 promoter induction. Therefore, the TCF4E C terminus harbors a promoter- specific transactivation domain. Tcf- 4 expression is sustained, whereas Lef- 1 levels fall... / Synonyms: TCF-4; TCF4B; TCF4E
Xenopus (Silurana) tropicalis
Gene: Synonyms: tcf-4
Xenopus laevis
Gene: Synonyms: tcf-4
Homo sapiens
Gene: ... - expression of N- cadherin, ICAT or dnTCF- 4 in isolated human VSMCs significantly lowered levels of cyclin D1 mRNA and protein levels. N- cadherin, ICAT or dnTCF- 4 over- expression significantly reduced... / Synonyms: Inhibitor of beta-catenin and Tcf-4
Danio rerio
Gene: ... High impact information on tcf4 In embryos, we find that the tcf4 gene is highly regulated at the level of RNA splicing such that the variant proteins that are produced contain or lack domains proposed to be essential in repression or activation of transcription. Expression of tcf4 mRNA is first detected...
Macaca mulatta


Links to contributing authors: Steven Johnsen and Donald R. Forsdyke and Kehinde Ross and Andrew Perry and Jonathan Eisen and A. Shimabukuro-Vornhagen and Giuseppe Rotondo and Gordon Laurie and Berkley Lynch and Kung-Hao Liang and Matthias Gstaiger and Thomas Pfeiffer and Marta Ramirez and Grant MacGregor and Jingyu Li and Fedik Rahimov and M El Gizouli and Marta Ramirez Gaite and Oswaldo Ribeiro-filho and Ralf Weigel and Bjoern Hamberger and Alexander Kanitz and Andreas Zankl and Chunming Ding and Maruf Yunus and Jonathan S. Berg and Michael Cariaso and Zakir Thomas and Monique Timberlake-Brady and LC Dore and Nan Shen and R. Eric Collins and Kuang-Mao Chiang and Brendan McMahon and John Chew and Wen-Ming Yang and Robert Hoffmann and J.B. Stewart and Manuela Cucerea and Ignacio García and William James and Thomas Kelder and Gregory Melahn and YINGDE ZHU and Andres Muro and Gabriel Santpere and Jeff Freilich and Junbin Qian and Steffen Poulsen and Eric Villard and Rafael Sidi and Grant Cramer and Chris Sander and Alexandre Chigaev and Florian Uhle and Carl Fulp and Andrew Brown and Xiaozhu Zhou and Corina Dutu and Hilary Spencer and david germano and Abbas Dehghan and Eung-ju PARK and Chris Sander and Albert Vilella and Miao Tian and Anjali Bheda and Michael Nevels and Jun Liu and D Delano and Chitose Taya and Soomi Cheong and David Kavanagh and Maha Karnoub and Hilmar Lapp and Christian Pallasch and Daniel Mietchen and Biju Balakrishnan and Keith Ashman and Juan Carlos Sobrino and Anshu Bhardwaj and Grzegorz Wickiel and Matthew Day and Anthony Sebastian and Vedran Katavic and Liang Long and Barry Wanner and Sarah Snelling and Fernando Montanes and Omobosede Fashedemi and Gustavo Cervantes and Manoj Kumar and Edward D Great and Paul Paukstelis and Roy Soetikno and Ana I Caño-Delgado and Minsoo Choi and Lei Wang and Brenda Riley and A Michelle Moon and Jon Moulton and Mahmoud Elshahawy and Meagan Gillespie and Banundari Rachmawati and Qian Han and Eric Danner and Xavier Fouillet and Madhusudhan Acharya and Brian Young and Chandra Sekhar Mukhopadhyay and shrawan bhattacharjee and Marieke van der Linden and cj hoban and Sandi Pniauskas and jackie gao and Metin Bilgin and Gillian L. Dalgliesh and Karl Wotton and Iveta Herichova and Yuji Morita and Marta Hernandez and Gregor Krings and Marco Briones and Tim D. Smith and Yiumo Michael Chan and Zhenyu Guo and Barry Barclay and Hong Wang and tarali chowdhury and Tilman Brummer and Nuno Faria and Tamir Ben David and Myles Axton and Yannick Fonseca and Francis Castets and Modesto Redrejo-Rodríguez and Bruce Herron and Toshio Fujita and Elena Puccetti and Zhang Zhang and John Osborne and Illes J Farkas and Fernando Andres and Phyllis Pugh and Jonathan Court and Tim Vickers and Nir Friedman and Holger Dick and Ya-Chen Liang and Jonathan Froehlich and Haitham Sobhy and David Abraham and Stephane Krief and Yaroslav Nikolaev and Qiping Feng and d gupta and R Thapar and Susan Wee and Michael Rehman and SOUMITRA GHOSH and Mohamed Eweida and Cedric Uytingco and Nie hongchuan and David Steenblock and Mark A. Kukucka and Zoli Fekete and Sergei Kozlov and Javier Jara and Osama Naguib and Felix Benninger and jean-marc lo-guidice and VASUDEVA BHAT and Anne O. Summers and Bjoern Titz and Anna Levine and Klas Udekwu and Robert Hoffmann
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