Tomohisa Hirobe
Radiation Effect Mechanisms Research Group
National Institute of Radiological Sciences
Anagawa
Inage-ku
Japan
Name/email consistency: high
- The mouse pink-eyed dilution allele of the P-gene greatly inhibits eumelanin but not pheomelanin synthesis. Hirobe, T., Ito, S., Wakamatsu, K. Pigment. Cell. Melanoma. Res (2011)
- Life cycle of human melanocytes is regulated by endothelin-1 and stem cell factor in synergy with cyclic AMP and basic fibroblast growth factor. Hirobe, T., Shinpo, T., Higuchi, K., Sano, T. J. Dermatol. Sci. (2010)
- Estrogen increases hair pigmentation in female recessive yellow mice. Hirobe, T., Kiuchi, M., Wakamatsu, K., Ito, S. Zool. Sci. (2010)
- Ferrous ferric chloride stimulates the skin cell function and hair growth in mice. Hirobe, T. Biol. Pharm. Bull. (2009)
- Mitochondria are more numerous and smaller in pink-eyed dilution melanoblasts and melanocytes than in wild-type melanocytes in the neonatal mouse epidermis. Hirobe, T., Ishizuka, K., Ogawa, S., Abe, H. Zool. Sci. (2008)
- Changes of melanosome morphology associated with the differentiation of epidermal melanocytes in slaty mice. Hirobe, T., Abe, H. Anat. Rec. (Hoboken) (2007)
- Excess tyrosine stimulates eumelanin and pheomelanin synthesis in cultured slaty melanocytes from neonatal mouse epidermis. Hirobe, T., Wakamatsu, K., Ito, S. Zool. Sci. (2007)
- Interleukin-1alpha stimulates the differentiation of melanocytes but inhibits the proliferation of melanoblasts from neonatal mouse epidermis. Hirobe, T., Ootaka, H. Zool. Sci. (2007)
- Excess tyrosine restores the morphology and maturation of melanosomes affected by the murine slaty mutation. Hirobe, T., Abe, H. Zool. Sci. (2007)
- Excess tyrosine rescues the reduced activity of proliferation and differentiation of cultured recessive yellow melanocytes derived from neonatal mouse epidermis. Hirobe, T., Abe, H., Wakamatsu, K., Ito, S., Kawa, Y., Soma, Y., Mizoguchi, M. Eur. J. Cell Biol. (2007)
- The eumelanin and pheomelanin contents in dorsal hairs of female recessive yellow mice are greater than in male. Hirobe, T., Wakamatsu, K., Ito, S. J. Dermatol. Sci. (2007)
- The slaty mutation affects eumelanin and pheomelanin synthesis in mouse melanocytes. Hirobe, T., Wakamatsu, K., Ito, S., Kawa, Y., Soma, Y., Mizoguchi, M. Eur. J. Cell Biol. (2006)
- The slaty mutation affects the morphology and maturation of melanosomes in the mouse melanocytes. Hirobe, T., Abe, H. Pigment Cell Res. (2006)
- Role of keratinocyte-derived factors involved in regulating the proliferation and differentiation of mammalian epidermal melanocytes. Hirobe, T. Pigment Cell Res. (2005)
- Hepatocyte growth factor controls the proliferation of cultured epidermal melanoblasts and melanocytes from newborn mice. Hirobe, T., Osawa, M., Nishikawa, S. Pigment Cell Res. (2004)
- Granulocyte-macrophage colony-stimulating factor (GM-CSF) controls the proliferation and differentiation of mouse epidermal melanocytes from pigmented spots induced by ultraviolet radiation B. Hirobe, T., Furuya, R., Hara, E., Horii, I., Tsunenaga, M., Ifuku, O. Pigment Cell Res. (2004)
- Granulocyte-macrophage colony-stimulating factor is a keratinocyte-derived factor involved in regulating the proliferation and differentiation of neonatal mouse epidermal melanocytes in culture. Hirobe, T., Furuya, R., Ifuku, O., Osawa, M., Nishikawa, S. Exp. Cell Res. (2004)
- Pheomelanin production in the epidermis from newborn agouti mice is induced by the expression of the agouti gene in the dermis. Hirobe, T., Takeuchi, S., Hotta, E., Wakamatsu, K., Ito, S. Pigment Cell Res. (2004)
- The melanocortin receptor-1 gene but not the proopiomelanocortin gene is expressed in melanoblasts and contributes their differentiation in the mouse skin. Hirobe, T., Takeuchi, S., Hotta, E. Pigment Cell Res. (2004)
- Effects of carbon-ion radiation on the postnatal development of mice and on the yield of white spots in the mid-ventrum and tail tips. Hirobe, T., Eguchi-Kasai, K., Murakami, M. Radiat. Res. (2004)
- Changes in the proliferation and differentiation of neonatal mouse pink-eyed dilution melanocytes in the presence of excess tyrosine. Hirobe, T., Wakamatsu, K., Ito, S. Pigment Cell Res. (2003)
- Steel factor controls the proliferation and differentiation of neonatal mouse epidermal melanocytes in culture. Hirobe, T., Osawa, M., Nishikawa, S. Pigment Cell Res. (2003)
- Effects of genic substitution at the pink-eyed dilution locus on the proliferation and differentiation of mouse epidermal melanocytes in vivo and in vitro. Hirobe, T., Kawa, Y., Mizoguchi, M., Ito, S., Wakamatsu, K. J. Exp. Zool. (2002)
- Stimulation of the proliferation and differentiation of mouse pink-eyed dilution epidermal melanocytes by excess tyrosine in serum-free primary culture. Hirobe, T., Wakamatsu, K., Ito, S., Abe, H., Kawa, Y., Mizoguchi, M. J. Cell. Physiol. (2002)
- Role of leukemia inhibitory factor in the regulation of the proliferation and differentiation of neonatal mouse epidermal melanocytes in culture. Hirobe, T. J. Cell. Physiol. (2002)
- Keratinocytes control the proliferation and differentiation of cultured epidermal melanocytes from ultraviolet radiation B-induced pigmented spots in the dorsal skin of hairless mice. Hirobe, T., Furuya, R., Akiu, S., Ifuku, O., Fukuda, M. Pigment Cell Res. (2002)
- Endothelins are involved in regulating the proliferation and differentiation of mouse epidermal melanocytes in serum-free primary culture. Hirobe, T. J. Investig. Dermatol. Symp. Proc. (2001)
- ACTH(4-12) is the minimal message sequence required to induce the differentiation of mouse epidermal melanocytes in serum-free primary culture. Hirobe, T., Abe, H. J. Exp. Zool. (2000)
- Genetic and epigenetic control of the proliferation and differentiation of mouse epidermal melanocytes in culture. Hirobe, T., Abe, H. Pigment Cell Res. (1999)
