Benito Alcaide
Grupo de Lactamas y Heterociclos Bioactivos
Departamento de Química Orgánica I
Unidad Asociada al CSIC
Facultad de Química
Spain
Name/email consistency: high
- Direct allenol-based stereocontrolled access to substituted (E)-1,3-enynes. Alcaide, B., Almendros, P., Martínez del Campo, T. Org. Biomol. Chem. (2012)
- Striking alkenol versus allenol reactivity: metal-catalyzed chemodifferentiating oxycyclization of enallenols. Alcaide, B., Almendros, P., Martínez del Campo, T., Redondo, M.C., Fernández, I. Chemistry (2011)
- Heterocyclization of allenes catalyzed by late transition metals: mechanisms and regioselectivity. Alcaide, B., Almendros, P., Del Campo, T.M., Soriano, E., Marco-Contelles, J. Top. Curr. Chem (2011)
- Fascinating reactivity in gold catalysis: synthesis of oxetenes through rare 4-exo-dig allene cyclization and infrequent β-hydride elimination. Alcaide, B., Almendros, P., Del Campo, T.M., Fernández, I. Chem. Commun. (Camb.) (2011)
- Controlled Rearrangement of Lactam-Tethered Allenols with Brominating Reagents: A Combined Experimental and Theoretical Study on α- versus β-Keto Lactam Formation. Alcaide, B., Almendros, P., Luna, A., Cembellín, S., Arnó, M., Domingo, L.R. Chemistry (2011)
- Cross-coupling/cyclization reactions of two different allenic moieties. Alcaide, B., Almendros, P., Martínez del Campo, T. Chemistry (2010)
- Exploiting [2+2] cycloaddition chemistry: achievements with allenes. Alcaide, B., Almendros, P., Aragoncillo, C. Chem. Soc. Rev (2010)
- Metal-catalyzed cycloetherification reactions of β,γ- and γ,δ-allendiols: chemo-, regio-, and stereocontrol in the synthesis of oxacycles. Alcaide, B., Almendros, P., Carrascosa, R., Martínez del Campo, T. Chemistry (2010)
- Rhodium-catalyzed synthesis of 3-hydroxy-beta-lactams via oxonium ylide generation: three-component reaction between azetidine-2,3-diones, ethyl diazoacetate, and alcohols. Alcaide, B., Almendros, P., Aragoncillo, C., Callejo, R., Ruiz, M.P., Torres, M.R. J. Org. Chem. (2009)
- Metal-catalyzed cyclization of beta- and gamma-allenols derived from D-glyceraldehyde--synthesis of enantiopure dihydropyrans and tetrahydrooxepines: an experimental and theoretical study. Alcaide, B., Almendros, P., Martínez del Campo, T., Soriano, E., Marco-Contelles, J.L. Chemistry (2009)
- Generating complexity from simplicity: Pd-catalyzed or Cu-promoted domino alkyne homocoupling/double [2+2] allenyne cycloaddition. Alcaide, B., Almendros, P., Aragoncillo, C. Chemistry (2009)
- Lewis acid-assisted ene cyclization of 2-azetidinone-tethered enals: synthesis of enantiopure carbacepham derivatives. Alcaide, B., Almendros, P., Pardo, C., Rodríguez-Ranera, C., Rodríguez-Vicente, A. Chem. Asian. J (2009)
- Regioselectivity control in the metal-catalyzed O-C functionalization of gamma-allenols, part 1: Experimental study. Alcaide, B., Almendros, P., Martínez del Campo, T., Soriano, E., Marco-Contelles, J.L. Chemistry (2009)
- Regioselectivity control in the metal-catalyzed functionalization of gamma-allenols, part 2: Theoretical study. Alcaide, B., Almendros, P., Martínez del Campo, T., Soriano, E., Marco-Contelles, J.L. Chemistry (2009)
- Chemo- and regioselective palladium-catalyzed oxycyclization reactions of allendiols: preparation of five-, six-, and eight-membered cycles. Alcaide, B., Almendros, P., Carrascosa, R., Martínez del Campo, T. Chemistry (2009)
- Grubbs' ruthenium-carbenes beyond the metathesis reaction: less conventional non-metathetic utility. Alcaide, B., Almendros, P., Luna, A. Chem. Rev. (2009)
- Organocatalytic reactions with acetaldehyde. Alcaide, B., Almendros, P. Angew. Chem. Int. Ed. Engl. (2008)
- I2-Catalyzed enantioselective ring expansion of beta-lactams to gamma-lactams through a novel C3-C4 bond cleavage. Direct entry to protected 3,4-dihydroxypyrrolidin-2-one derivatives. Alcaide, B., Almendros, P., Cabrero, G., Ruiz, M.P. Chem. Commun. (Camb.) (2008)
- Stereoselective NaN3-catalyzed halonitroaldol-type reaction of azetidine-2,3-diones in aqueous media. Alcaide, B., Almendros, P., Luna, A., Torres, M.R. Org. Biomol. Chem. (2008)
- New regiocontrolled synthesis of functionalized pyrroles from 2-azetidinone-tethered allenols. Alcaide, B., Almendros, P., Carrascosa, R., Redondo, M.C. Chemistry (2008)
- Synthesis of novel enantiopure 4-hydroxypipecolic acid derivatives with a bicyclic beta-lactam structure from a common 3-azido-4-oxoazetidine-2-carbaldehyde precursor. Alcaide, B., Almendros, P., Luna, A., Martínez del Campo, T. J. Org. Chem. (2008)
- Chemodivergence in alkene/allene cycloetherification of enallenols: iron versus noble metal catalysis. Alcaide, B., Almendros, P., Martínez del Campo, T. Chemistry (2008)
- Pd(II)-catalyzed domino heterocyclization/cross-coupling of alpha-allenols and alpha-allenic esters: efficient preparation of functionalized buta-1,3-dienyl dihydrofurans. Alcaide, B., Almendros, P., Martínez Del Campo, T., Carrascosa, R. Chemistry, An Asian J. (2008)
- Direct organocatalytic synthesis of enantiopure succinimides from beta-lactam aldehydes through ring expansion promoted by azolium salt precatalysts. Alcaide, B., Almendros, P., Cabrero, G., Ruiz, M.P. Chem. Commun. (Camb.) (2007)
- Carbonyl allenylation/free radical cyclization sequence as a new regio- and stereocontrolled access to bi- and tricyclic beta-lactams. Alcaide, B., Almendros, P., Aragoncillo, C., Redondo, M.C. J. Org. Chem. (2007)
- Stereocontrolled access to orthogonally protected anti,anti-4-aminopiperidine-3,5-diols through chemoselective reduction of enantiopure beta-lactam cyanohydrins. Alcaide, B., Almendros, P., Cabrero, G., Ruiz, M.P. J. Org. Chem. (2007)
- Beta-lactams: versatile building blocks for the stereoselective synthesis of non-beta-lactam products. Alcaide, B., Almendros, P., Aragoncillo, C. Chem. Rev. (2007)
- Metal-catalyzed regiodivergent cyclization of gamma-allenols: tetrahydrofurans versus oxepanes. Alcaide, B., Almendros, P., Martínez del Campo, T. Angew. Chem. Int. Ed. Engl. (2007)
- Synthesis of strained tricyclic beta-lactams by intramolecular [2+2] cycloaddition reactions of 2-azetidinone-tethered enallenols: control of regioselectivity by selective alkene substitution. Alcaide, B., Almendros, P., Aragoncillo, C., Redondo, M.C., Torres, M.R. Chemistry (2006)
- A practical ruthenium-catalyzed cleavage of the allyl protecting group in amides, lactams, imides, and congeners. Alcaide, B., Almendros, P., Alonso, J.M. Chemistry (2006)
- Efficient entry to diversely functionalized spirocyclic oxindoles from isatins through carbonyl-addition/cyclization reaction sequences. Alcaide, B., Almendros, P., Rodríguez-Acebes, R. J. Org. Chem. (2006)
- Proline-catalyzed diastereoselective direct aldol reaction between 4-oxoazetidine-2-carbaldehydes and ketones. Alcaide, B., Almendros, P., Luna, A., Torres, M.R. J. Org. Chem. (2006)
- Domino metal-free allene-beta-lactam-based access to functionalized pyrroles. Alcaide, B., Almendros, P., Redondo, M.C. Chem. Commun. (Camb.) (2006)
- Novel carbonyl bromoallylation/Heck reaction sequence. Stereocontrolled access to bicyclic beta-lactams. Alcaide, B., Almendros, P., Rodríguez-Acebes, R. J. Org. Chem. (2005)
- Pd-Cu bimetallic catalyzed domino cyclization of alpha-allenols followed by a coupling reaction: new sequence leading to functionalized spirolactams. Alcaide, B., Almendros, P., Rodríguez-Acebes, R. Chemistry (2005)
- Organocatalytic ring expansion of beta-lactams to gamma-lactams through a novel N1-C4 bond cleavage. direct synthesis of enantiopure succinimide derivatives. Alcaide, B., Almendros, P., Cabrero, G., Ruiz, M.P. Org. Lett. (2005)
- Diastereoselectivity enhancement in the 1,3-cycloaddition of beta-lactam aldehydes. Application to the synthesis of enantiopure indolizidinone amino esters. Alcaide, B., Almendros, P., Redondo, M.C., Ruiz, M.P. J. Org. Chem. (2005)
- Straightforward asymmetric entry to highly functionalized 3-substituted 3-hydroxy-beta-lactams via Baylis-Hillman or bromoallylation reactions. Alcaide, B., Almendros, P., Aragoncillo, C., Rodríguez-Acebes, R. J. Org. Chem. (2004)
- Synthesis of optically pure highly functionalized gamma-lactams via 2-azetidinone-tethered iminophosphoranes. Alcaide, B., Almendros, P., Alonso, J.M. J. Org. Chem. (2004)
- Novel N1-C4 beta-lactam bond breakage. Synthesis of enantiopure alpha-alkoxy-gamma-keto acid derivatives. Alcaide, B., Almendros, P., Redondo, M.C. Org. Lett. (2004)
- Beta-lactams as versatile synthetic intermediates for the preparation of heterocycles of biological interest. Alcaide, B., Almendros, P. Curr. Med. Chem. (2004)
- Asymmetric synthesis of unusual fused tricyclic beta-lactam structures via aza-cycloadditions/ring closing metathesis. Alcaide, B., Almendros, P., Alonso, J.M., Redondo, M.C. J. Org. Chem. (2003)
- The direct catalytic asymmetric cross-aldol reaction of aldehydes. Alcaide, B., Almendros, P. Angew. Chem. Int. Ed. Engl. (2003)
- Non-metathetic behavior patterns of Grubbs' carbene. Alcaide, B., Almendros, P. Chemistry (2003)
- Lewis acid-promoted intermolecular carbonyl-ene reaction of enantiopure 4-oxoazetidine-2-carbaldehydes. Rapid entry to novel fused polycyclic beta-lactams. Alcaide, B., Almendros, P., Pardo, C., Rodríguez-Ranera, C., Rodríguez-Vicente, A. J. Org. Chem. (2003)
- Useful dual Diels-Alder behavior of 2-azetidinone-tethered aryl imines as azadienophiles or azadienes: a beta-lactam-based stereocontrolled access to optically pure highly functionalized indolizidine systems. Alcaide, B., Almendros, P., Alonso, J.M., Aly, M.F. Chemistry (2003)
- Structurally novel Bi- and tricyclic beta-lactams via [2 + 2] cycloaddition or radical reactions in 2-azetidinone-tethered enallenes and allenynes. Alcaide, B., Almendros, P., Aragoncillo, C. Org. Lett. (2003)
- Ruthenium-catalyzed chemoselective N-allyl cleavage: novel Grubbs carbene mediated deprotection of allylic amines. Alcaide, B., Almendros, P., Alonso, J.M. Chemistry (2003)
- Metal-mediated carbonyl-1,3-butadien-2-ylation by 1,4-bis(methanesulfonyl)-2-butyne or 1,4-dibromo-2-butyne in aqueous media: asymmetric synthesis of 3-substituted 3-hydroxy-beta-lactams. Alcaide, B., Almendros, P., Rodríguez-Acebes, R. J. Org. Chem. (2002)
- Additions of allenyl/propargyl organometallic reagents to 4-oxoazetidine-2-carbaldehydes: novel palladium-catalyzed domino reactions in allenynes. Alcaide, B., Almendros, P., Aragoncillo, C. Chemistry (2002)
- New domino transposition/intramolecular Diels-Alder reaction in monocyclic allenols: a general strategy for tricyclic compounds. Alcaide, B., Almendros, P., Aragoncillo, C., Redondo, M.C. Chem. Commun. (Camb.) (2002)
- A novel one-step approach for the preparation of alpha-amino acids, alpha-amino amides, and dipeptides from azetidine-2,3-diones. Alcaide, B., Almendros, P., Aragoncillo, C. Chemistry (2002)
- A novel use of Grubbs' carbene. Application to the catalytic deprotection of tertiary allylamines. Alcaide, B., Almendros, P., Alonso, J.M., Aly, M.F. Org. Lett. (2001)
- Rapid entry to enantiopure carbacepham derivatives via Lewis acid promoted carbonyl-ene cyclization of 2-azetidinone-tethered alkenylaldehydes. Alcaide, B., Pardo, C., Rodríguez-Ranera, C., Rodríguez-Vicente, A. Org. Lett. (2001)
