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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Michael F. Jarvis

R-4DI AP9A/3111

Early Discovery

Pain Abbott Laboratories

100 Abbott Park Rd.

USA. Electronic address:


Name/email consistency: high



  • R-4DI AP9A/3111, Early Discovery, Pain Abbott Laboratories, 100 Abbott Park Rd., USA. Electronic address:. 2012
  • Neuroscience Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, USA. 2002 - 2010
  • Abbott Laboratories, 100 Abbott Park Road, Abbott Park, IL 60064, USA. 2001 - 2009
  • Neurological and Urological Diseases Research and Metabolic Diseases Research, Pharmaceutical Products Division, Abbott Laboratories, 100 Abbott Park Road, USA. 2000


  1. Cytochrome P450 mediated linoleic acid metabolism in peripheral inflammatory nociception. Jarvis, M.F. Pain (2012) [Pubmed]
  2. The neural-glial purinergic receptor ensemble in chronic pain states. Jarvis, M.F. Trends Neurosci. (2010) [Pubmed]
  3. ATP-gated P2X cation-channels. Jarvis, M.F., Khakh, B.S. Neuropharmacology (2009) [Pubmed]
  4. A-803467, a potent and selective Nav1.8 sodium channel blocker, attenuates neuropathic and inflammatory pain in the rat. Jarvis, M.F., Honore, P., Shieh, C.C., Chapman, M., Joshi, S., Zhang, X.F., Kort, M., Carroll, W., Marron, B., Atkinson, R., Thomas, J., Liu, D., Krambis, M., Liu, Y., McGaraughty, S., Chu, K., Roeloffs, R., Zhong, C., Mikusa, J.P., Hernandez, G., Gauvin, D., Wade, C., Zhu, C., Pai, M., Scanio, M., Shi, L., Drizin, I., Gregg, R., Matulenko, M., Hakeem, A., Gross, M., Johnson, M., Marsh, K., Wagoner, P.K., Sullivan, J.P., Faltynek, C.R., Krafte, D.S. Proc. Natl. Acad. Sci. U.S.A. (2007) [Pubmed]
  5. [3H]A-317491, a novel high-affinity non-nucleotide antagonist that specifically labels human P2X2/3 and P2X3 receptors. Jarvis, M.F., Bianchi, B., Uchic, J.T., Cartmell, J., Lee, C.H., Williams, M., Faltynek, C. J. Pharmacol. Exp. Ther. (2004) [Pubmed]
  6. Contributions of P2X3 homomeric and heteromeric channels to acute and chronic pain. Jarvis, M.F. Expert Opin. Ther. Targets (2003) [Pubmed]
  7. Antagonism of P2X3-containing channels: commentary on Spelta et al. Jarvis, M.F., Burgard, E.C. Br. J. Pharmacol. (2002) [Pubmed]
  8. Analgesic and anti-inflammatory effects of A-286501, a novel orally active adenosine kinase inhibitor. Jarvis, M.F., Yu, H., McGaraughty, S., Wismer, C.T., Mikusa, J., Zhu, C., Chu, K., Kohlhaas, K., Cowart, M., Lee, C.H., Stewart, A.O., Cox, B.F., Polakowski, J., Kowaluk, E.A. Pain (2002) [Pubmed]
  9. Comparison of the ability of adenosine kinase inhibitors and adenosine receptor agonists to attenuate thermal hyperalgesia and reduce motor performance in rats. Jarvis, M.F., Mikusa, J., Chu, K.L., Wismer, C.T., Honore, P., Kowaluk, E.A., McGaraughty, S. Pharmacol. Biochem. Behav. (2002) [Pubmed]
  10. A-317491, a novel potent and selective non-nucleotide antagonist of P2X3 and P2X2/3 receptors, reduces chronic inflammatory and neuropathic pain in the rat. Jarvis, M.F., Burgard, E.C., McGaraughty, S., Honore, P., Lynch, K., Brennan, T.J., Subieta, A., Van Biesen, T., Cartmell, J., Bianchi, B., Niforatos, W., Kage, K., Yu, H., Mikusa, J., Wismer, C.T., Zhu, C.Z., Chu, K., Lee, C.H., Stewart, A.O., Polakowski, J., Cox, B.F., Kowaluk, E., Williams, M., Sullivan, J., Faltynek, C. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  11. Modulation of BzATP and formalin induced nociception: attenuation by the P2X receptor antagonist, TNP-ATP and enhancement by the P2X(3) allosteric modulator, cibacron blue. Jarvis, M.F., Wismer, C.T., Schweitzer, E., Yu, H., van Biesen T, , Lynch, K.J., Burgard, E.C., Kowaluk, E.A. Br. J. Pharmacol. (2001) [Pubmed]
  12. ABT-627, an endothelin ET(A) receptor-selective antagonist, attenuates tactile allodynia in a diabetic rat model of neuropathic pain. Jarvis, M.F., Wessale, J.L., Zhu, C.Z., Lynch, J.J., Dayton, B.D., Calzadilla, S.V., Padley, R.J., Opgenorth, T.J., Kowaluk, E.A. Eur. J. Pharmacol. (2000) [Pubmed]
  13. ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive effects in the mouse. Jarvis, M.F., Yu, H., Kohlhaas, K., Alexander, K., Lee, C.H., Jiang, M., Bhagwat, S.S., Williams, M., Kowaluk, E.A. J. Pharmacol. Exp. Ther. (2000) [Pubmed]
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