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Pierre-Louis Toutain

UMR1331 Toxalim Physiologie

Ecole Nationale Veterinaire de Toulouse

23 Chemin des Capelles




Name/email consistency: high



  • UMR1331 Toxalim Physiologie, Ecole Nationale Veterinaire de Toulouse, 23 Chemin des Capelles, BP87614, France. 2011
  • UMR181 Physiopathologie et Toxicologie Expérimentales INRA, ENVT, 23 Chemin des Capelles, 31076 Toulouse cedex 03, France. 2001 - 2010
  • Unité Mixte de Recherche 181 Physiopathologie et Toxicologie Expérimentales, Institut National de la Recherche Agronomique et Ecole Nationale Vétérinaire de Toulouse, 23 Chemin des Capelles, BP 87 614, France. 2010
  • Ecole Nationale Vétérinaire de Toulouse, et Institut National de la Recherche Agronomique, Unité Associée de Physiopathologie et Toxicologie Expérimentales, Toulouse, France. 2000 - 2002


  1. Paw inflammation model in dogs for preclinical pharmacokinetic/pharmacodynamic investigations of nonsteroidal anti-inflammatory drugs. Jeunesse, E.C., Bargues, I.A., Toutain, C.E., Lacroix, M.Z., Letellier, I.M., Giraudel, J.M., Toutain, P.L. J. Pharmacol. Exp. Ther. (2011) [Pubmed]
  2. Species differences in pharmacokinetics and pharmacodynamics. Toutain, P.L., Ferran, A., Bousquet-Mélou, A. Handb. Exp. Pharmacol (2010) [Pubmed]
  3. Veterinary medicines and competition animals: the question of medication versus doping control. Toutain, P.L. Handb. Exp. Pharmacol (2010) [Pubmed]
  4. AUC/MIC: a PK/PD index for antibiotics with a time dimension or simply a dimensionless scoring factor? Toutain, P.L., Bousquet-Mélou, A., Martinez, M. J. Antimicrob. Chemother. (2007) [Pubmed]
  5. Plasma clearance. Toutain, P.L., Bousquet-Mélou, A. J. Vet. Pharmacol. Ther. (2004) [Pubmed]
  6. Plasma terminal half-life. Toutain, P.L., Bousquet-Mélou, A. J. Vet. Pharmacol. Ther. (2004) [Pubmed]
  7. Volumes of distribution. Toutain, P.L., Bousquet-Mélou, A. J. Vet. Pharmacol. Ther. (2004) [Pubmed]
  8. Bioavailability and its assessment. Toutain, P.L., Bousquet-Mélou, A. J. Vet. Pharmacol. Ther. (2004) [Pubmed]
  9. Integration and modelling of pharmacokinetic and pharmacodynamic data to optimize dosage regimens in veterinary medicine. Toutain, P.L., Lees, P. J. Vet. Pharmacol. Ther. (2004) [Pubmed]
  10. Pharmacokinetics and pharmacokinetic/pharmacodynamic relationships for angiotensin-converting enzyme inhibitors. Toutain, P.L., Lefèbvre, H.P. J. Vet. Pharmacol. Ther. (2004) [Pubmed]
  11. The pharmacokinetic-pharmacodynamic approach to a rational dosage regimen for antibiotics. Toutain, P.L., del Castillo, J.R., Bousquet-Mélou, A. Res. Vet. Sci. (2002) [Pubmed]
  12. Pharmacokinetic/pharmacodynamic integration in drug development and dosage-regimen optimization for veterinary medicine. Toutain, P.L. AAPS. PharmSci (2002) [Pubmed]
  13. Pharmacokinetic profile and in vitro selective cyclooxygenase-2 inhibition by nimesulide in the dog. Toutain, P.L., Cester, C.C., Haak, T., Metge, S. J. Vet. Pharmacol. Ther. (2001) [Pubmed]
  14. A pharmacokinetic/pharmacodynamic approach vs. a dose titration for the determination of a dosage regimen: the case of nimesulide, a Cox-2 selective nonsteroidal anti-inflammatory drug in the dog. Toutain, P.L., Cester, C.C., Haak, T., Laroute, V. J. Vet. Pharmacol. Ther. (2001) [Pubmed]
  15. Benazeprilat disposition and effect in dogs revisited with a pharmacokinetic/pharmacodynamic modeling approach. Toutain, P.L., Lefebvre, H.P., King, J.N. J. Pharmacol. Exp. Ther. (2000) [Pubmed]
  16. New insights on effect of kidney insufficiency on disposition of angiotensin-converting enzyme inhibitors: case of enalapril and benazepril in dogs. Toutain, P.L., Lefebvre, H.P., Laroute, V. J. Pharmacol. Exp. Ther. (2000) [Pubmed]
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