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Chemical Compound Review

Dillapiol     4,5-dimethoxy-6-prop-2-enyl- benzo[1,3]dioxole

Synonyms: Dillapiole, Dill apiole, CHEMBL470874, SureCN310992, Dill apiol, ...
 
 
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High impact information on Dill apiole

  • The resolution of dillapiole and dihydrodillapiole has been achieved on RP-18 column using methanol-water (90:10, v/v) as mobile phase and a photodiode array detector at 207 nm [1].
  • In vivo activity was improved by (1) incorporation into an easy to absorb suspension, (2) preparation of a more stable compound, 7-methoxygedunin; and (3) synergism with dillapiol, a cytochrome P450 3A4 inhibitor [2].
 

Analytical, diagnostic and therapeutic context of Dill apiole

  • Preparative HPLC with 5-micrometer silica allowed isolation of gram quantities of parsleyapiole and dillapiole from extracts of plain parsley seeds and dill seeds, respectively [3].

References

  1. Liquid chromatographic method for the analysis of two plant based insecticide synergists dillapiole and dihydrodillapiole. Walia, S., Saha, S., Parmar, B.S. Journal of chromatography. A. (2004) [Pubmed]
  2. Traditionally-used antimalarials from the Meliaceae. Omar, S., Zhang, J., MacKinnon, S., Leaman, D., Durst, T., Philogene, B.J., Arnason, J.T., Sanchez-Vindas, P.E., Poveda, L., Tamez, P.A., Pezzuto, J.M. Current topics in medicinal chemistry. (2003) [Pubmed]
  3. High-pressure liquid chromatographic separation of the naturally occurring toxicants myristicin, related aromatic ethers and falcarinol. Wulf, L.W., Nagel, C.W., Branen, A.L. J. Chromatogr. (1978) [Pubmed]
 
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