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Chemical Compound Review

Altertoxin-I     (12S,12aR,12bR)-4,9,12,12b- tetrahydroxy-2...

Synonyms: Altertoxin I, CHEMBL521470, CCRIS 2190, KST-1A6183, AC1L2XMQ, ...
 
 
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High impact information on Altertoxin I

  • Alterperylenol inhibited telomerase activity (IC50 = 30 microM), but altertoxin I, a structurally related compound, did not affect it at 1 mM [1].
 

Analytical, diagnostic and therapeutic context of Altertoxin I

References

  1. Inhibition of human telomerase activity by alterperylenol. Togashi, K., Kakeya, H., Morishita, M., Song, Y.X., Osada, H. Oncol. Res. (1998) [Pubmed]
  2. Selective determination of altertoxins by high-performance liquid chromatography with electrochemical detection with dual "in-series" electrodes. Visconti, A., Sibilia, A., Palmisano, F. J. Chromatogr. (1991) [Pubmed]
 
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