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Chemical Compound Review:

alpha-Tetralol 1,2,3,4-tetrahydronaphthalen- 1-ol

Synonyms: Tetralin-1-ol, SureCN59026, CHEMBL357784, NSC-5172, ACMC-209g2q, ...

Sheng, J.J. et al., Ferrante, A.A. et al.

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High impact information on tetralin-1-ol

The ahpC mutant was found to have an activity that was three times that of the wild type in reducing tetralin hydroperoxide to 1,2,3,4-tetrahydro-1-naphthol [1].
Previous work discovered a stereospecificity of AST IV toward the enantiomers of 1,2,3,4-tetrahydro-1-naphthol and varying degrees of stereoselectivity with other chiral benzylic alcohols [2].

References

Cloning of an organic solvent-resistance gene in Escherichia coli: the unexpected role of alkylhydroperoxide reductase. Ferrante, A.A., Augliera, J., Lewis, K., Klibanov, A.M. Proc. Natl. Acad. Sci. U.S.A. (1995) [Pubmed]
Influence of phenylalanines 77 and 138 on the stereospecificity of aryl sulfotransferase IV. Sheng, J.J., Saxena, A., Duffel, M.W. Drug Metab. Dispos. (2004) [Pubmed]

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