The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

LS-52415     4-[(3R,5R,10S,13R,14S,17S)- 3,14-dihydroxy...

Synonyms: AC1L1WG2, 545-52-8, epi-Digitoxigenin, 3-Epidigitoxigenin, 3-alpha-Digitoxigenin, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on epi-Digitoxigenin

  • By separation of different sulfotransferases it was found that the hydroxysteroid-ST is responsible for dt-0 and 3-epidigitoxigenin (epi-dt-0) sulfation [1].
  • The four stereoisomers of the 2-hydroxy derivatives of digitoxigenin and 3-epidigitoxigenin have been synthesized, their structures established by NMR, and their binding affinity for the digitalis receptor on Na+, K(+)-ATPase evaluated [2].

References

  1. Hydroxysteroid sulfotransferase and a specific UDP-glucuronosyltransferase are involved in the metabolism of digitoxin in man. Schmoldt, A., Blömer, I., Johannes, A. Naunyn Schmiedebergs Arch. Pharmacol. (1992) [Pubmed]
  2. Synthesis and biological evaluation of 2-hydroxy derivatives of digitoxigenin and 3-epidigitoxigenin. Gobbini, M., Marazzi, G., Padoani, G., Quadri, L., Valentino, L., Zappavigna, M.P., Melloni, P. Bioorg. Med. Chem. (1998) [Pubmed]
 
WikiGenes - Universities