Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

C08840 (3S,5S,9R,10R,13S,14R,17R)- 17-[(2S,5S)-5...

Synonyms:

Cristiano, R. et al., Zhang, L.J. et al., Villaseñor, I.M. et al.

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High impact information on C08840

From the roots of Securidaca inappendiculata, one new sterol glycoside securisteroside (1) has been isolated, along with two known sterols, spinasterol (2) and 3-O-beta-D-glucopyranosyl-spinasterol (3) [1].
By posterior analysis of an apolar crude extract using high resolution gas chromatography coupled to mass spectrometry (HRGC-MS) it was possible to characterize two sterol (spinasterol and delta25-spinasterol) and the minor 1-hydroxy-2,3,5-trimethoxyxanthone (3) [2].

Analytical, diagnostic and therapeutic context of C08840

Spinasterol, an antimutagen, was isolated from squash flowers by solvent partitioning and repeated vacuum liquid chromatography [3].

References

A new sterol glycoside from Securidaca inappendiculata. Zhang, L.J., Yang, X.D., Xu, L.Z., Zou, Z.M., Yang, S.L. Journal of Asian natural products research. (2005) [Pubmed]
Two xanthones from Polygala paniculata and confirmation of the 1-hydroxy-2,3,5-trimethoxy-xanthone at trace level by HRGC-MS. Cristiano, R., Pizzolatti, M.G., Delle Monache, F., Rezende, C.M., Branco, A. Z. Naturforsch., C, J. Biosci. (2003) [Pubmed]
Anticarcinogenicity potential of spinasterol isolated from squash flowers. Villaseñor, I.M., Domingo, A.P. Teratog., Carcinog. Mutagen. (2000) [Pubmed]

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