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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
Chemical Compound Review

AG-F-78304     3-methyl-2- (3,7,11,15,19,23,27,31...

Synonyms: AG-K-68773, SureCN14164340, AC1L1AWW, CTK5J8838, CTK8G0790
 
 
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High impact information on vitamin K2

  • On the fifth postnatal day, mean levels of VK1 (p less than 0.01) and VK2 (p less than 0.01) in breast milk were significantly higher in the VK1 and VK2 treated mothers than in the control mothers, respectively [1].
  • On the other hand, VK2 and GGO induce apoptosis but most likely by some other unknown pathway [2].
 

Analytical, diagnostic and therapeutic context of vitamin K2

  • Similarly, these levels were significantly elevated in cord plasma in VK1 (p less than 0.05) and VK2 (p less than 0.05) treated groups, compared with findings in the control group, although there was a large concentration gradient between maternal and cord plasma (mostly less than one-tenth) [1].

References

  1. Oral supplementation of vitamin K for pregnant women and effects on levels of plasma vitamin K and PIVKA-II in the neonate. Motohara, K., Takagi, S., Endo, F., Kiyota, Y., Matsuda, I. J. Pediatr. Gastroenterol. Nutr. (1990) [Pubmed]
  2. Cytotoxic effect through fas/APO-1 expression due to vitamin K in human glioma cells. Sun, L.K., Yoshii, Y., Miyagi, K. J. Neurooncol. (2000) [Pubmed]
 
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