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Chemical Compound Review

o-Iodoaniline     2-iodoaniline

Synonyms: zlchem 529, PubChem10573, SureCN74028, I7004_ALDRICH, ACMC-1BEWY, ...
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High impact information on NSC 34544

  • Interaction of 2-iodoaniline or 5-fluoro-2-iodoaniline with a range of arylsulfonyl chlorides affords sulfonamides that undergo Sonogashira couplings under thermal or microwave conditions with the alkyne 4-ethynyl-4-hydroxycyclohexa-2,5-dien-1-one followed by cyclization to 4-[1-(arylsulfonyl-1H-indol-2-yl)]-4-hydroxycyclo-hexa-2,5-dien-1-ones [1].
  • A simple three-step preparation of polymer-supported N-(2-iodyl-phenyl)-acylamide (NIPA resin) starting from 2-iodoaniline is described [2].


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