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Chemical Compound Review

NAADP     1-[(2R,3R,4S,5R)-5- [[[[(2R,3R,4R,5R)-5-(6...

Synonyms: NAADP+, NAADP(1+), CHEBI:76072, AC1L3XLY, C13051, ...
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High impact information on C13051

  • Picomolar concentrations of bombesin and CCK evoked similar patterns of cytosolic Ca2+ oscillations, but high, desensitising, NAADP concentrations selectively inhibited CCK, but not bombesin-evoked signals [1].

Anatomical context of C13051

  • It was reported recently that nicotinic acid adenine dinucleotide phosphate (NAADP) releases Ca2+ from mammalian brain microsomes [5] and triggers Ca2+ signals in pancreatic acinar cells, where it is proposed to mediate CCK-evoked Ca2+ signals [6] [1].


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