Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Claramax

Synonyms: Clarinex, Denosin, Desalex, Aerius, Azomyr, ...

Canonica, G.W. et al., Pradalier, A. et al.

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Disease relevance of Clarinex

Analysis of objective data on nasal blockage demonstrated a significant improvement in nasal airflow with desloratadine, when compared with placebo (SMD 0.32; 95% CI 0.10 to 0.55; P = 0.005) [1].
Significant reductions in signs and symptoms of AR with desloratadine treatment were accompanied by improved disease-specific QOL measures [2].

References

Efficacy of desloratadine in the treatment of allergic rhinitis: a meta-analysis of randomized, double-blind, controlled trials. Canonica, G.W., Tarantini, F., Compalati, E., Penagos, M. Allergy (2007) [Pubmed]
Desloratadine improves quality of life and symptom severity in patients with allergic rhinitis. Pradalier, A., Neukirch, C., Dreyfus, I., Devillier, P. Allergy (2007) [Pubmed]

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