Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

AC1L2OMK (5R,6R)-7-ethyl-5-(3- hydroxyphenyl)carbony...

Synonyms:

Steele, B.W. et al., Oyler, J. et al.

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High impact information on m-Hydroxybenzoylecgonine

The presence of p-hydroxybenzoylecgonine in meconium suggested that this newly identified metabolite, like m-hydroxybenzoylecgonine, might serve as a valuable marker of fetal cocaine exposure during pregnancy [1].
Results before and after hydrolysis with beta-glucuronidase (type IX) showed free m-hydroxybenzoylecgonine comprising 59 to 94% of the total m-hydroxybenzoylecgonine and showed total m-hydroxybenzoylecgonine values ranging from 0.2 to 6.3 times as high as benzoylecgonine [2].

References

Cocaine disposition in meconium from newborns of cocaine-abusing mothers and urine of adult drug users. Oyler, J., Darwin, W.D., Preston, K.L., Suess, P., Cone, E.J. Journal of analytical toxicology. (1996) [Pubmed]
m-Hydroxybenzoylecgonine: an important contributor to the immunoreactivity in assays for benzoylecgonine in meconium. Steele, B.W., Bandstra, E.S., Wu, N.C., Hime, G.W., Hearn, W.L. Journal of analytical toxicology. (1993) [Pubmed]

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