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Chemical Compound Review: 

SureCN6255527     4-[(2,5-dihydroxyphenyl) methylamino]benzamide

Synonyms: ACMC-20mwnv, RG-14467, CTK0I0113, AC1L30CE, RG 14467, ...
 
 
 
 
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High impact information on RG 14467

  • When studied with the least protective peptide, K1 (a peptide containing the major autophosphorylation site of the EGF receptor), RG 14467 acts as a hyperbolic noncompetitive inhibitor with respect to the peptide [1].

References

  1. Kinetic analysis of the inhibition of the epidermal growth factor receptor tyrosine kinase by Lavendustin-A and its analogue. Hsu, C.Y., Persons, P.E., Spada, A.P., Bednar, R.A., Levitzki, A., Zilberstein, A. J. Biol. Chem. (1991) [Pubmed]
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