Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Phe-pro-arg (2S)-2-[[(2S)-1-[(2R)-2- amino-3-phenyl...

Synonyms: SureCN2119635, AC1Q5JRX, AR-1I7027, AC1L32CF, 79338-56-0, ...

Bagdy, D. et al., de Lamirande, E. et al.

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High impact information on Phenylalanyl-prolyl-arginine

Some inhibitors, including aprotinin, boc-gln-leu-lys-H, and D-phe-pro-arg-H, could inhibit motility as well as prevent initiation of motility [1].
Comparative studies on the anticoagulant effect of D-Phe-Pro-Arg-H (ALD) and D-Phe-Pro-Arg-CH2Cl (CMK) were carried out in order to estimate whether the reversible or the irreversible tripeptide inhibitor of thrombin would be more suitable to develop as a novel anticoagulant [2].

References

Effects of protease inhibitors and substrates on motility of mammalian spermatozoa. de Lamirande, E., Gagnon, C. J. Cell Biol. (1986) [Pubmed]
Comparative studies in vitro and ex vivo on the anticoagulant effect of a reversible and an irreversible tripeptide inhibitor of thrombin. Bagdy, D., Barabás, E., Bajusz, S., Széll, E., Fehér, A. Thromb. Res. (1992) [Pubmed]

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