Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

Sarasar

Synonyms: Lonafarnib, SureCN19032, CHEMBL298734, cc-590, Sch-66336, ...

Sun, S.Y. et al.

Shi-Yong Sun, Xiangguo Liu, Wei Zou, Ping Yue, Adam I. Marcus, Fadlo R. Khuri,

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Associations of Sarasar with other chemical compounds

Lonafarnib up-regulated DR5 expression, increased cell-surface DR5 distribution, and enhanced tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis [1].

References

The farnesyltransferase inhibitor lonafarnib induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells. Sun, S.Y., Liu, X., Zou, W., Yue, P., Marcus, A.I., Khuri, F.R. J. Biol. Chem. (2007) [Pubmed]

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