Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Chemical Compound Review:

SureCN249514 6-hydroxy-5-methyl-1,3- diazinane-2,4-dione

Synonyms: AG-D-71949, CTK4B9678, AKOS006351687, AC1L4736, 13514-92-6, ...

Zuo, S. et al., Ganguly, T. et al.

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Disease relevance of Thymine hydrate

Thymine hydrate stabilities were studied in irradiated DNA substrates using purified E. coli endonuclease III as a reagent for their removal [1].

Associations of Thymine hydrate with other chemical compounds

Similarly, incubation of UV-irradiated poly(dA-dT) with endonuclease III did not release thymine hydrate; nonenzymatic release of thymine occurred [2].

References

Stability of DNA thymine hydrates. Ganguly, T., Duker, N.J. Nucleic Acids Res. (1991) [Pubmed]
Comparison of the effects of UV irradiation on 5-methyl-substituted and unsubstituted pyrimidines in alternating pyrimidine-purine sequences in DNA. Zuo, S., Boorstein, R.J., Cunningham, R.P., Teebor, G.W. Biochemistry (1995) [Pubmed]

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